Medi-Weightloss Franchise Costs, Fees, Profit and Data for 2025
Franchise Opportunity Deep Dive: Medi-Weightloss is a leading brand in physician-supervised weight loss, offering science-backed, physician-led services to combat the obesity epidemic.
Medi-Weightloss is a nationally recognized franchise specializing in non-surgical, physician-supervised weight management. Known for its evidence-based programs and clinical oversight, the brand offers a trusted solution for individuals seeking long-term weight loss support. Backed by private equity firm Audax Group and based in Tampa, Florida, the brand has helped clients lose over 9.2 million pounds.
1. What Is the Brand Overview for Medi-Weightloss?
About the Brand
The company was founded in 2005 in Tampa, Florida, by Edward Kaloust, in collaboration with a team of physicians and health care professionals. It began franchising shortly after its founding and has since grown into a leading name in medical weight loss. In 2025, Brian Petranick — former group president at Neighborly and CEO of Right at Home* — was appointed CEO to guide the brand’s next phase of growth.
Mission: To fight the obesity epidemic in America through science-backed, physician-supervised weight loss programs.
Vision: To be the leading provider of evidence-based weight loss and wellness services in the United States.
Unique Selling Points (USPs)
Medically supervised and clinically proven programs
Proprietary supplements and nutritional products
Vitamin and nutrient injections, IV therapy, and prescription solutions
Individualized care plans and long-term maintenance programs
Pediatric weight loss services for ages 12-18
2. What Are the Franchise Opportunity Details?
Why Franchise With Medi-Weightloss?
Proven business model and national brand recognition
Protected territories and turnkey clinic model
Comprehensive training, marketing, and compliance support
Revenue streams from consultations, products, and in-office therapies
Flexibility to operate as a medical professional or management entity
Available Territories
Medi-Weightloss offers large protected territories throughout the U.S. with room for further expansion. Visit the brand's website to inquire about available markets.
Investment Overview
Initial Costs: The estimated initial investment required to begin operation of a Medi-Weightloss franchise ranges from $251,000 to $494,000. The 2025 Franchise Disclosure Document (FDD) breaks these costs down as follows:
Type of Expenditure
Min
Max
Initial Franchise Fee
$60,000
$60,000
Initial Package
$49,000
$54,000
Training Fee
$15,000
$15,000
Furniture, Fixtures, Equipment & Supplies
$15,000
$35,000
Lease Payments (3 Months)
$7,000
$15,000
Leasehold Improvements
$30,000
$125,000
Real Estate & Construction Project Management Services
$0
$20,000
Architecture Fees & Permits
$1,000
$4,500
Computer System
$2,000
$3,000
Security Deposits
$3,500
$10,000
Additional Inventory & Supplies
$1,000
$5,000
Signage
$6,000
$8,000
Licenses & Permits
$500
$1,500
Insurance
$5,000
$15,000
Professional Fees
$2,000
$10,000
Training Travel Expenses
$4,000
$8,000
Grand Opening Marketing Campaign
$15,000
$15,000
Local Advertising (3 Months)
$15,000
$20,000
Optional IV Therapy Program
$0
$10,000
Additional Funds (3 Months)
$20,000
$60,000
Initial Franchise Fee: The franchise fee is $60,000, which is payable upon signing the franchise agreement. Area developers pay reduced per-unit fees based on the number of franchises.
Ongoing Fees: According to the 2025 FDD, Medi-Weightloss franchisees are responsible for the following ongoing payments and fees:
Type of Fee
Amount
Royalty Fee
Greater of $2,250 or 10% of gross sales/month
System Branding Fund
Greater of $250/ or 1% of gross sales/month
Local Marketing Spend Required
$5,000/month (rolling six-month basis)
ROI Potential: According to the 2025 FDD, the 57 businesses operating for the entirety of FY 2024 reported the following gross profit:
Reporting Businesses
Average
Median
High
Low
Top Third (19)
$1,307,115
$1,179,985
$2,238,129
$633,638
Middle Third (19)
$696,584
$697,507
$866,778
$521,673
Bottom Third (19)
$379,952
$388,700
$514,067
$174,197
TOTAL (57)
$794,551
$727,113
$2,238,129
$174,197
3. What Franchisee Support Does Medi-Weightloss Provide?
Training Programs
In-person training at headquarters in Tampa, Florida
Ongoing on-site training and eLearning
Educational resources and compliance audits
Operational Support
Grand opening campaign execution
On-call operations and clinic management support
Regional and national advertising support
Technology and Tools
Practice management software
EMR and prescription labeling systems
Online ordering platform and HIPAA-compliant systems
4. What Are the Franchise Requirements for Medi-Weightloss?
Eligibility Criteria
Health care professionals can operate directly (Health Care Business)
Non-licensed investors can manage the business (Management Business) with licensed medical providers handling patient care
Operational Commitments
Full-time management recommended
Clinic must comply with all medical regulations and HIPAA laws
Funding Assistance
No in-house financing offered
Franchisees are encouraged to consult legal and financial professionals
5. Are There Franchisee Success Stories?
“The revenue generation has exceeded our expectations without question. It’s a challenge in figuring out, as any business model grows, how do you grow at a proper pace, to change your operations and to be able to handle the load.”
Medi-Weightloss sets itself apart with a physician-supervised, science-based approach to weight management, offering a turn-key franchise model with exclusive territories, proprietary EMR software and multiple revenue streams through programs like diabetes care and corporate wellness. Backed by strong operational support and clinical credibility, the brand delivers both proven outcomes and a scalable business model.
7. What Is the Application Process for Medi-Weightloss Franchisees?
Introductory Call and Business Overview Presentation: Kick things off with an initial call to learn about the brand, its model and how the opportunity aligns with your goals.
Documents Review: Review the FDD, complete an NDA and submit your franchise application to begin due diligence.
Leadership Meetings: Meet with team members from Operations, Medical Affairs and Marketing to dive deeper into the support and structure of the system.
Deeper-Dive Call: Reconnect with the franchise team to address remaining questions, explore available territories and assess next steps.
Validation Calls With Current Franchisees: Speak with existing owners to gain real-world insights into the franchise experience and performance.
Day of Discovery: Visit Medi‑Weightloss headquarters in Tampa to meet leadership, tour the facility and experience the brand firsthand.
Agreement Review: Receive and review your personalized franchise agreement, outlining all commitments and expectations before signing.
Welcome to the Team: Once the agreement is signed, you officially begin onboarding, training and preparation to open your Medi‑Weightloss clinic.
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