Franchisor Stories
Franchise Opportunity Deep Dive: Prime IV Hydration & Wellness provides a leading IV therapy franchise within the booming wellness market featuring a proven model, support and recurring revenue.
Prime IV Hydration & Wellness is a leading IV therapy franchise offering a range of intravenous vitamin and hydration treatments in a spa-like setting.
Prime IV Hydration & Wellness was founded in Colorado Springs, Colorado, by a team of wellness professionals passionate about helping people achieve optimal health through IV hydration and vitamin therapy. Since its founding, the brand has grown rapidly into one of the nation’s largest and most recognized IV therapy franchises, now spanning over 240 units across 42 states.
Mission: To help individuals take control of their health by providing cutting-edge IV hydration therapy that supports vitality, recovery, and overall wellness.
Vision: To redefine preventative health and wellness by making IV hydration therapy accessible and transformative in every community.
Prime IV is expanding nationwide, with prime markets available across the United States. Complete and submit the inquiry form on the Prime IV franchising website for more information on available territories.
Initial Costs: The estimated initial investment for a Prime IV Hydration & Wellness franchise ranges from $190,501 to $632,193. The 2025 Franchise Disclosure Document (FDD) breaks these costs down as follows:
| Type of Expenditure | Min | Max |
| Initial Franchise Fee | $49,000 | $49,000 |
| Security Deposits | $5,000 | $8,000 |
| Lease Expenses (3 Months) | $6,000 | $30,000 |
| Leasehold Improvements | $23,000 | $320,000 |
| Architecture & Design | $500 | $5,000 |
| Signage & Displays | $7,500 | $10,000 |
| Office Equipment | $20,000 | $38,000 |
| Other Required Spa Equipment | $1,137 | $4,426 |
| Medical Equipment & Supplies | $15,000 | $60,000 |
| Supplies (Blood Pressure Cuff, Temporal Scanner, Pulse/OX, Office or Medical) | $500 | $500 |
| Inventory | $5,000 | $10,000 |
| Medical or Clinical Director Salary (3 Months) | $0 | $5,400 |
| Medical Support Salaries (3 Months) | $9,000 | $18,000 |
| Training Expenses | $2,500 | $3,500 |
| Security System (Setup & 3 Months) | $500 | $2,500 |
| Telephone System | $300 | $500 |
| Business Licenses & Permits | $700 | $5,000 |
| Professional Fees | $1,000 | $10,000 |
| Computer System | $1,000 | $5,000 |
| Technology Fee (Setup & 3 Months) | $747 | $747 |
| POS System | $945 | $945 |
| EMR System (Setup & 3 Months) | $225 | $375 |
| Accounting Software | $147 | $300 |
| Insurance Deposits & Premiums | $3,500 | $5,000 |
| Pre-Opening Operations | $2,500 | $7,000 |
| Grand Opening & Initial Marketing | $17,000 | $17,000 |
| Additional Funds (3 Months) | $15,000 | $15,000 |
Initial Franchise Fee: The Initial Franchise Fee is $49,000 per location, payable in full upon signing the franchise agreement.
Discounts include:
Ongoing Fees: According to the 2025 FDD, Prime IV franchisees are responsible for the following ongoing costs and fees:
| Type of Fee | Amount |
| Royalty Fee | 7% of gross revenues/month |
| Branding Fund Contribution | 2% of gross revenues/month |
| Technology Fee | Up to $250/month |
| Local Marketing | Minimum of $1,000/month |
ROI Potential: According to the 2025 FDD, the Prime IV franchises open for at least 12 months in 2022, 2023 and 2024 reported the following gross sales:
Average | Median | High | Low | |
| 2022 (31) | $534,770 | $507,815 | $1,333,179 | $101,930 |
| 2023 (49) | $698,937 | $662,046 | $1,402,185 | $242,543 |
| 2024 (99) | $567,075 | $539,234 | $1,426,456 | $148,651 |
3. What Franchisee Support Does Prime IV Provide?
Prime IV provides extensive pre-opening training at headquarters and onsite. Training covers operational management, compliance with medical and safety standards, hiring and certification of licensed staff, and customer service.
Franchisees receive hands-on guidance for site selection, lease negotiation, spa design, grand opening and local marketing. Corporate field consultants and a dedicated franchise development team provide ongoing operational coaching.
Franchisees benefit from a fully integrated POS and membership system, a robust CRM for client engagement, and compliance management tools that ensure adherence to USP 797 safety standards for IV preparation and administration.
No medical background required; owners hire licensed medical staff (typically an RN and medical director).
Prime IV allows for both owner-operator and semi-absentee models. Most franchisees oversee management and marketing while their trained staff handles day-to-day operations.
Prime IV offers introductions to third-party lenders familiar with its franchise model. Franchisees may also qualify for SBA loans and veterans’ financing programs.
“I’ve been open approximately two months now, already covering my costs and on my way to profitability. I love the concept — it’s a wonderful addition to health and wellness, and seeing clients come back raving about how they feel is so rewarding.”
- Stacia Politowicz, Franchisee — New Smyrna Beach, Florida
The IV hydration and wellness industry was estimated at $2.64 billion in 2024 and is projected to reach $5.66 billion by 2033, growing at a CAGR of 9.0% from 2025 to 2033. This expansion shows a rising demand for holistic health. Consumers, especially professionals, athletes and wellness-focused individuals, want preventative solutions. Prime IV is well-positioned as a market leader. It offers a unique, medically supervised, spa-like experience.
Competitor Analysis
Key competitors include Restore Hyper Wellness, IV Drip Bar and The Hydration Room, but Prime IV differentiates itself through its upscale design, medically backed protocols, and strong national brand recognition.
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